Floor E Jansen Selected Research

Focal Cortical Dysplasia

12/2021	The epileptogenic zone in children with tuberous sclerosis complex is characterized by prominent features of focal cortical dysplasia.
10/2021	Balloon cells promote immune system activation in focal cortical dysplasia type 2b.
1/2021	Upregulation of the pathogenic transcription factor SPI1/PU.1 in tuberous sclerosis complex and focal cortical dysplasia by oxidative stress.
1/2021	GATOR1-related focal cortical dysplasia in epilepsy surgery patients and their families: A possible gradient in severity?
1/2019	Oxidative stress and inflammation in a spectrum of epileptogenic cortical malformations: molecular insights into their interdependence.
1/2019	The landscape of epilepsy-related GATOR1 variants.
12/2009	Doublecortin-like (DCL) expression in focal cortical dysplasia and cortical tubers.
6/2009	Expression patterns of synaptic vesicle protein 2A in focal cortical dysplasia and TSC-cortical tubers.

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Floor E Jansen Research Topics

Disease

40	Tuberous Sclerosis (Bourneville's Disease) 11/2022 - 03/2005
34	Epilepsy (Aura) 01/2022 - 03/2005
18	Seizures (Absence Seizure) 01/2022 - 11/2004
11	Drug Resistant Epilepsy 01/2022 - 01/2006
8	Focal Cortical Dysplasia 12/2021 - 06/2009
7	Inborn Genetic Diseases (Disease, Hereditary) 01/2022 - 09/2016
6	Intellectual Disability (Idiocy) 01/2022 - 01/2017
6	Autism Spectrum Disorder 01/2022 - 10/2018
6	Brain Diseases (Brain Disorder) 11/2020 - 11/2015
5	Astrocytoma (Pilocytic Astrocytoma) 11/2022 - 11/2017
4	Inflammation (Inflammations) 10/2021 - 01/2016
4	Autistic Disorder (Autism) 01/2020 - 01/2017
2	Brain Neoplasms (Brain Tumor) 11/2022 - 11/2017
2	Neurodevelopmental Disorders 10/2021 - 01/2020
2	Partial Epilepsies (Epilepsy, Partial) 01/2021 - 01/2016
2	Myoclonic Epilepsies (Myoclonic Encephalopathy) 01/2021 - 05/2009
2	Neurocutaneous Syndromes (Phakomatoses) 02/2020 - 01/2020
2	Hamartoma 01/2020 - 01/2016
2	Carcinogenesis 01/2020 - 06/2018
2	Generalized Epilepsy 12/2019 - 01/2016
2	Status Epilepticus (Complex Partial Status Epilepticus) 06/2019 - 02/2016
2	Temporal Lobe Epilepsy 01/2018 - 11/2013
1	Cysts 12/2021
1	Sleepiness 01/2021
1	Diarrhea 01/2021
1	Congenital, Hereditary, and Neonatal Diseases and Abnormalities (Congenital Disorders) 01/2021
1	Epileptic Syndromes 11/2020
1	Cognitive Dysfunction 10/2020
1	Infantile Spasms (West Syndrome) 02/2020
1	Spasm (Spasms) 02/2020
1	Hydrocephalus (Hydrocephaly) 01/2020
1	Encephalitis (Encephalitis, Rasmussen) 01/2019
1	Learning Disabilities (Learning Disability) 01/2019
1	Hemimegalencephaly 01/2019
1	Neuroinflammatory Diseases 01/2019
1	Neurologic Manifestations (Neurological Manifestations) 10/2018
1	Ganglioglioma 06/2018
1	Glioblastoma (Glioblastoma Multiforme) 06/2018
1	Glioma (Gliomas) 06/2018
1	Hippocampal Sclerosis 01/2018
1	Nervous System Diseases (Neurological Disorders) 11/2016
1	Gliosis 01/2016
1	Whooping Cough (Pertussis) 08/2015
1	Hallucinations (Hallucination) 07/2012
1	Convulsions benign familial neonatal dominant form 02/2010
1	Malformations of Cortical Development 12/2009
1	Febrile Seizures (Febrile Seizure) 05/2009

Drug/Important Bio-Agent (IBA)

40	trans-sodium crocetinate (crocetin)IBA 11/2022 - 03/2005
6	Mechanistic Target of Rapamycin Complex 1IBA 10/2021 - 01/2016
6	Anticonvulsants (Antiepileptic Drugs)IBA 01/2021 - 11/2004
5	TOR Serine-Threonine KinasesIBA 10/2021 - 01/2016
5	Pharmaceutical PreparationsIBA 01/2021 - 01/2016
4	Biomarkers (Surrogate Marker)IBA 01/2022 - 11/2017
4	Hydrocortisone (Cortisol)FDA LinkGeneric 01/2018 - 06/2015
3	Sirolimus (Rapamycin)FDA Link 11/2022 - 09/2016
3	Vigabatrin FDA Link 01/2021 - 01/2020
3	Proteins (Proteins, Gene)FDA Link 10/2020 - 06/2009
3	SteroidsIBA 02/2020 - 11/2015
2	Bumetanide (Bumex)FDA LinkGeneric 01/2022 - 01/2020
2	Biological ProductsIBA 01/2021 - 01/2018
2	CannabidiolIBA 01/2021 - 02/2020
2	AutoantibodiesIBA 11/2020 - 01/2017
2	Everolimus FDA Link 02/2020 - 01/2019
2	Ion Channels (Ion Channel)IBA 12/2019 - 02/2010
2	MicroRNAs (MicroRNA)IBA 06/2018 - 01/2018
2	Interleukin-6 (Interleukin 6)IBA 01/2018 - 04/2016
2	Hormones (Hormone)IBA 01/2016 - 06/2015
1	ChloridesIBA 01/2022
1	Cell Adhesion MoleculesIBA 01/2022
1	Transcription Factors (Transcription Factor)IBA 01/2021
1	RNA (Ribonucleic Acid)IBA 01/2021
1	Methylprednisolone FDA LinkGeneric 11/2020
1	Clobazam (HR 376)IBA 11/2020
1	Prednisolone (Predate)FDA LinkGeneric 11/2020
1	Adrenal Cortex Hormones (Corticosteroids)IBA 11/2020
1	Matrix Metalloproteinases (MMPs)IBA 01/2020
1	Peptide Elongation Factors (Elongation Factor)IBA 01/2020
1	Vitamin B 6IBA 12/2019
1	AntioxidantsIBA 01/2019
1	DNA (Deoxyribonucleic Acid)IBA 04/2018
1	Interleukin-1beta (Interleukin 1 beta)IBA 01/2018
1	gamma-Aminobutyric Acid (GABA)IBA 03/2017
1	Monoclonal AntibodiesIBA 01/2017
1	Rituximab (Mabthera)FDA Link 01/2017
1	AMPA Receptors (AMPA Receptor)IBA 11/2016
1	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 04/2016
1	CytokinesIBA 02/2016
1	Combined VaccinesIBA 08/2015
1	VaccinesIBA 08/2015
1	Inactivated VaccinesIBA 10/2014
1	Attenuated VaccinesIBA 10/2014
1	Valproic Acid (Depakote)FDA LinkGeneric 07/2012
1	Sodium Channels (Sodium Channel)IBA 05/2009

Therapy/Procedure

3	Therapeutics 10/2021 - 06/2018
1	Treatment Delay 01/2021
1	Electrodes (Electrode) 11/2013